Adrien Nicholas Brody was born in Woodhaven, Queens, New York, the only child of retired history professor Elliot Brody and Hungarian-born photographer Sylvia Plachy. He accompanied his mother on assignments for the Village Voice, and credits her with making him feel comfortable in front of the camera. Adrien attended the American Academy of Dramatic Arts and LaGuardia High School for the Performing Arts in New York.
| Movie | Evolution of the Species: Predators Reborn | Self | 2027 |
| Movie | Motor City | 2025-08-30 | |
| Movie | The Brutalist | László Tóth | 2024-12-20 |
| Movie | Fool's Paradise | Chad Luxt | 2023-05-12 |
| Movie | Ghosted | Leveque | 2023-04-18 |
| Movie | Asteroid City | Schubert Green | 2023-06-08 |
| Movie | Manodrome | Dan | 2023-11-10 |
| Movie | Clean | Clean | 2022-01-28 |
| Series | Winning Time: The Rise of the Lakers Dynasty | Pat Riley | 2022-03-06 |
| Movie | Blonde | The Playwright | 2022-09-16 |
| Movie | See How They Run | Leo Köpernick | 2022-09-09 |
| Series | Chapelwaite | Captain Charles Boone | 2021-08-22 |
| Movie | The French Dispatch of the Liberty, Kansas Evening Sun | Julian Cadazio | 2021-10-21 |
| Movie | Trintignant by Trintignant | Self (archive footage) | 2021-10-11 |
| Movie | Spider-Man: Far From Home | Norman Osborn | 2019-06-28 |
| Movie | Air Strike | Steve | 2018-10-26 |
| Movie | Who Will Write Our History? | Emanuel Ringelblum (voice) | 2018-07-21 |
| Movie | Bullet Head | Stacy | 2017-12-07 |
| Movie | Manhattan Night | Porter Wren | 2016-05-20 |
| Movie | The Mascot | Adam | 2015-06-27 |
| Movie | Dragon Blade | Tiberius | 2015-02-19 |
| Movie | Boredom | Danny | 2015-06-27 |
| Movie | The Library Book | Desmond | 2015-06-27 |
| Movie | Backtrack | Peter Bower | 2015-07-25 |
| Movie | Septembers of Shiraz | Isaac | 2015-09-15 |
| Movie | And the Oscar Goes To... | Self (archive footage) | 2014-02-01 |
| Movie | The Grand Budapest Hotel | Dmitri | 2014-02-26 |
| Movie | American Heist | Frankie | 2014-09-11 |
| Movie | Third Person | Sean | 2014-06-20 |
| Series | Houdini | Harry Houdini | 2014-09-01 |
| Movie | InAPPropriate Comedy | Flirty Harry | 2013-03-22 |
| Series | Peaky Blinders | Luca Changretta | 2013-09-12 |
| Movie | Love, Marilyn | Self | 2013-05-30 |
| Movie | Back to 1942 | Theodore Harold White | 2012-11-01 |
| Movie | Roman Polanski: A Film Memoir | Self (archive footage) | 2012-10-09 |
| Movie | Midnight in Paris | Salvador Dalí | 2011-05-11 |
| Movie | Detachment | Henry Barthes | 2011-04-24 |
| Movie | Wrecked | Man | 2010-04-01 |
| Movie | Giallo | Inspector Enzo Avolfi | 2010-03-13 |
| Movie | Splice | Clive | 2010-06-03 |
| Movie | Predators | Royce | 2010-07-07 |
| Movie | The Making of 'The Darjeeling Limited' | Self - Peter | 2010-10-12 |
| Movie | The Experiment | Travis | 2010-07-15 |
| Movie | High School | Psycho Ed | 2010-06-03 |
| Movie | Fantastic Mr. Fox | Field Mouse (voice) | 2009-10-14 |
| Movie | Cadillac Records | Leonard Chess | 2008-12-05 |
| Movie | A Matador's Mistress | Manuel Rodríguez Sánchez "Manolete" | 2008-09-06 |
| Movie | The Brothers Bloom | Bloom | 2008-09-09 |
| Movie | Gumball 3000: Drivin' Me Crazy | Self | 2007-05-27 |
| Movie | The Darjeeling Limited | Peter | 2007-09-07 |
| Movie | Hollywoodland | Louis Simo | 2006-08-31 |
| Movie | Recreating the Eighth Wonder: The Making of 'King Kong' | Self | 2006-11-14 |
| Movie | The Jacket | Jack Starks | 2005-03-04 |
| Movie | Deconstructing 'The Village' | Self | 2005-01-11 |
| Movie | Gumball 3000: 6 Days in May | Self | 2005-05-09 |
| Movie | King Kong: Peter Jackson's Production Diaries | Self | 2005-12-13 |
| Movie | King Kong | Jack Driscoll | 2005-12-12 |
| Movie | The Village | Noah Percy | 2004-07-30 |
| Movie | The Buried Secret of M. Night Shyamalan | Self | 2004-06-18 |
| Movie | Love the Hard Way | Jack Grace | 2003-03-27 |
| Movie | The Singing Detective | First Hood | 2003-10-24 |
| Movie | The Pianist | Władysław 'Władek' Szpilman | 2002-09-17 |
| Movie | Dummy | Steven Schoichet | 2002-09-12 |
| Movie | The Affair of the Necklace | Count Nicolas De La Motte | 2001-11-30 |
| Movie | Ken and Rosa | Himself | 2001-10-25 |
| Movie | Restaurant | Chris Calloway | 2000-01-28 |
| Movie | Bread and Roses | Sam Shapiro | 2000-09-14 |
| Movie | Harrison's Flowers | Kyle Morris | 2000-09-23 |
| Movie | Liberty Heights | Van Kurtzman | 1999-11-17 |
| Movie | Six Ways to Sunday | Arnie Finklestein | 1999-03-05 |
| Movie | Summer of Sam | Ritchie | 1999-06-28 |
| Movie | Oxygen | Harry | 1999-11-12 |
| Movie | The Thin Red Line | Cpl. Geoffrey Fife | 1998-12-23 |
| Movie | Mythos Hollywood - Das Geheimnis des Erfolgs | Self | 1998-01-01 |
| Movie | The Undertaker's Wedding | Mario Bellini | 1997-01-01 |
| Movie | The Last Time I Committed Suicide | Ben | 1997-06-20 |
| Movie | Bullet | Ruby Stein | 1996-03-01 |
| Movie | Solo | Dr. Bill Stewart, Solo's Designer | 1996-08-23 |
| Movie | Ten Benny | Ray Diglovanni | 1995-04-09 |
| Movie | Angels in the Outfield | Danny Hemmerling | 1994-07-15 |
| Series | Rebel Highway | Skinny | 1994-07-07 |
| Movie | Jailbreakers | Skinny | 1994-09-09 |
| Movie | Natural Born Killers | Wayne Gale's Cameraman | 1994-08-26 |
| Movie | King of the Hill | Lester | 1993-08-20 |
| Movie | The Boy Who Cried Bitch | Eddie | 1991-10-11 |
| Movie | New York Stories | Mel | 1989-03-10 |
| Movie | Home at Last | Billy | 1988-01-09 |